Exercise-induced oxidative stress and antioxidant responses: A meta-analysis
Exercise-induced oxidative stress and antioxidant responses: A meta-analysis
Author(s): Hamza Hussain Ali Alsalihi
Abstract: Exercise has two positive effects on human physiology: it is a source of reactive oxygen species (ROS) and a stimulator of adaptive antioxidant defense mechanisms. The objectives of this meta-analysis were to provide the synthesis of available evidence on the topic of oxidative stress markers and its antioxidant responses in acute and chronic exercise. To determine the sources and variability of antioxidant response to physical stressing, we examine both the extent and effects of oxidative stress on the body, the effects of physical stressing on antioxidant responses in trained and untrained individuals, and the effects of supplementation. We see that both oxidative biomarkers increase after exercise, and both enzymatic and non- enzymatic antioxidant systems increase in general and specifically in trained animals or during a specific dietary intervention.
Hamza Hussain Ali Alsalihi. Exercise-induced oxidative stress and antioxidant responses: A meta-analysis. J Sports Sci Nutr 2025;6(2):21-30. DOI: 10.33545/27077012.2025.v6.i2a.328